Excess weight, in and of itself, is not a disease. When it comes to her patients, she says, shes a stickler for a holistic approach to health, including eating a nutritious diet (not just eating less) and daily physical activity, as essential elements of the weight-loss process
Understanding a patients baseline metabolic health reduces the risk of unexpected side effects and provides a safer environment for initiating therapy
However, this process revealed additional binding partners including proteins that regulate oxidative phosphorylation, mitochondrial membrane transport, the citric acid cycle, and glycolysis (Supplemental Table 1)
During trials, subjects started the dosage at 2mg once per week, injecting into the stomach or thigh area and slowly increasing the dosage per week or even split dosing the product twice a week